This book, now in its fourth edition, aims to promote a deeper understanding of the scientific and clinical basis of nuclear medicine and the new directions in medical imaging. The new edition has been revised and updated significantly to reflect recent changes and to ensure that the contents are in line with likely future directions. In addition to that, chapters have been reorganized in order to simplify the contents and to increase the readability. The book starts by providing essential information on general pathophysiology, cell biology and biologic effects of ionizing radiation followed by the mechanisms of radiopharmaceutical localization in different tissues and cells. This is followed by a series of chapters that covers all relevant organ systems presenting the basic knowledge of anatomy, physiology, and pathology and relating them to the clinical utilization of various scintigraphic modalities. The final chapter is devoted to the basis of therapeutic applications of nuclear medicine. The book will prove invaluable to all with an interest in the pathophysiologic basis of Nuclear Medicine, including nuclear medicine professionals, radiologists, surgeons, pediatricians and internal medicine physicians.

This invaluable and well-presented text brings together previously fragmented or incompletely elucidated data on the impressive recent advances in orthopedic nuclear medicine. The book begins by acquainting the readers with various anatomic, physiologic, pathologic and technical concepts crucial to understanding orthopedic nuclear medicine and its utilization in clinical practice. Subsequent chapters detail the diagnosis of skeletal infections, trauma, vascular disorders, metabolic and neoplastic bone diseases, soft tissue calcifications and joint disorders. A separate section is devoted to the use of radionuclides in the treatment of bone and joint diseases. A unique feature of this richly illustrated volume is its comprehensive and clinically oriented approach. The book will prove invaluable to all with an interest in diagnostic and therapeutic orthopedics, including radiologists, orthopedists, rheumatologists, pediatricians, other clinicians and nuclear medicine professionals.

The second edition of this book has been significantly expanded to meet the demands of the increasing new trend of molecular imaging. A separate chapter on the basis of FDG uptake has been added. New to this edition are the more clinically oriented details on scintigraphic studies, their strengths and limitations in relation to other modalities. It further contains many new images, illustrations and tables.

This book provides all the information required for the optimal use of nuclear medicine techniques, which are undergoing rapid development yet remain underutilized. Each chapter focuses on one particular clinical system or disease area. The first section of each chapter illustrates normal patterns observed on commonly and uncommonly performed scans as a reference and explains when and how the procedures should be performed. The following section illustrates both the imaging patterns of different diseases and the diagnostic role of individual studies. Comparisons with other modalities are provided, and the rationale for and effective utilization of each study are discussed. The volume includes near 250 case reviews. In addition, the normal patterns on relevant morphologic modalities are documented in an appendix. The book is directed at Nuclear Medicine physicians and technologists with different levels of training and expertise and also at radiologists who practice nuclear medicine and radiology residents.

This book, now in its fourth edition, aims to promote a deeper understanding of the scientific and clinical basis of nuclear medicine and the new directions in medical imaging. The new edition has been revised and updated significantly to reflect recent changes and to ensure that the contents are in line with likely future directions. In addition to that, chapters have been reorganized in order to simplify the contents and to increase the readability. The book starts by providing essential information on general pathophysiology, cell biology and biologic effects of ionizing radiation followed by the mechanisms of radiopharmaceutical localization in different tissues and cells. This is followed by a series of chapters that covers all relevant organ systems presenting the basic knowledge of anatomy, physiology, and pathology and relating them to the clinical utilization of various scintigraphic modalities. The final chapter is devoted to the basis of therapeutic applications of nuclear medicine. The book will prove invaluable to all with an interest in the pathophysiologic basis of Nuclear Medicine, including nuclear medicine professionals, radiologists, surgeons, pediatricians and internal medicine physicians.